provided evidence that the Gln27Glu polymorphism, though not the Arg16Gly variant, of the ADRB2 gene is associated with a broad spectrum of aging-related phenotypes, including various cancers, myocardial infarction (MI), intermittent claudication (IC), and both overall and healthy longevity. Here, ADRB2 is linked to myocardial infarction.