ITPR2 and type 2 diabetes mellitus: For example, rs6798160 in the ITPR2 gene showed the lowest P-value in the POE analysis, with an estimated POE by RRm/RRf of 0.11 (95% CI: 0.03–0.38), revealing that the SNP had a much lower impact when inherited from maternal (RRm) compared to that inherited from the paternal (RRf) on T2D.