SOCS2 and hemoglobin measurement: Similarly, our team discovered that the miR-181b/SOCS2/JAK2/STAT5 signaling axis shows that high expression of miR-181b in HB is positively correlated with tumor malignancy, promoting the activation of the JAK2/STAT5 signaling pathway by reducing SOCS2 expression levels, thereby driving the progression of HB.