KLF4 and neoplasm: Additionally, noncoding RNAs such as lncRNAs (CRNDE, MIR210HG, SNHG9, TUG1) and circRNAs (CDR1) interact with miRNAs (miR-7–5p, miR-608) to modulate the expression of downstream targets such as KLF4 and FOXO6, further influencing tumor stemness and malignancy.