The LASSO regression results identified 15 potential variables associated with IKPLAS, including: DM, Drink, Prior history of biliary disease, Hypertension, Underlying heart disease, Fever, PLT, CRP, AST, TBIL, Creatinine, Broth culture, Abscess location, Pleural effusion, and Ascites (Figure 2). This evidence concerns the gene CRP and Ascites.