Interestingly, genetic loss of FABP4 attenuated liver steatosis, inflammation, and fibrosis, as demonstrated by steatosis and lobular inflammation scores, lipid deposition, reduced expression of inflammatory and fibrotic genes, collagen deposition, α-SMA expression, F4/80 macrophages, and M1/M2 macrophage ratio (Supplemental Figure 3, A–H). Here, ACTA1 is linked to Hepatic steatosis.