CD81 and acute myeloid leukemia: Correspondingly, we observed an upregulation in the protein expression of lysophospholipid acyltransferases, including LPCAT1, LPCAT3, and LPCAT4 (Figure 6D), which catalyze the reacylation of lysophospholipids to phospholipids in AML cells cocultured with CD81+ Erys.