Similarly, depletion of KIF20A in another TNBC line, HCC1806, led to a reduction in CSC frequency (1:3,448 in KIF20A-KO vs. 1:604 in control group, P = 0.00944) (Figure 4C), accompanied by smaller tumor volumes especially in the 5,000 dilution group (Figure 4, D and E). Here, KIF20A is linked to neoplasm.