We investigated potential predictors for incident VFs, including the burden of prevalent vertebral fractures (number and Genant grade), prior osteoporosis treatment, lipid profile (e.g., triglycerides), low back pain VAS, physical function (timed-up-and-go, one-leg standing), and nutritional indices (e.g., albumin, selected nutrients from the Food Frequency Questionnaire). This evidence concerns the gene ALB and osteoporosis.