Furthermore, within tumor cell subsets, co-expression of ALKBH5 with LGR5 (R = 0.39, P < 0.0001; n = 1295 cells) and CD133 (R = 0.25, P < 0.0001; n = 2867 cells) were observed (Fig. S1E). Here, LGR5 is linked to neoplasm.