Among them, ALDH1B1 expression was higher in patients with metastatic recurrence compared to those without metastatic recurrence, while PTS and DGKI showed no differences in their expression between these patients (Fig. 1d and Supplementary Fig. 1f), suggesting that ALDH1B1 may play an important role in tumor metastasis. This evidence concerns the gene ALDH1B1 and neoplasm.