Moreover, the survival and the migratory capability of RelA-depleted cells were also greatly recovered by ALDH1B1 overexpression (Fig. 4l, m and Supplementary Fig. 7k, l), whereas RelA depletion showed no significant impact on lipid peroxidation or survival in unconfined tumor cells (Fig. 4k, l and Supplementary Fig. 7j, k). The gene discussed is RELA; the disease is neoplasm.