Previous studies have shown that MEK1/2 inhibitors improve cardiac phenotypes (Abe et al. 2024; Cuevas‐Navarro et al. 2023) and rescue embryonic lethality (Chen et al. 2010; Hernández‐Porras et al. 2014; Inoue et al. 2014) in RASopathy model mice. The gene discussed is MAP2K1; the disease is RASopathy.