Comparison between AD+sLATE– and AD+sLATE+ when controlling for Tau‐MaX and for the interval between tau‐PET and the baseline MRI scan in addition to age again revealed that the AD+sLATE+ group had a greater rate of atrophy than AD alone, most prominently and largely confined to medial and anterior temporal lobe regions, as well as orbitofrontal (Figure 3B IV). Here, MAPT is linked to Alzheimer disease.