To investigate the role of HDAC1 in microglial polarization following ischemic stroke, we examined the expression of pro-inflammatory (Figure 1) and anti-inflammatory (Figure 2) microglial markers in brain sections from Sham, Stroke, and Stroke + HDAC1 KD groups 3 days after brain ischemia induction. The gene discussed is HDAC1; the disease is ischemic stroke.