The findings indicated that that inflammation, signaled by CRP > 2 mg/L, amplified the susceptibility to AF independently of variables such age, gender, BMI, waist circumference, smoking, diabetes or hypertension status, history of CAD and HF, the use of medications for hypertension or statins, or prior chemotherapy—without evidence of effect modification (all P for interaction > 0.05) (Table 5). This evidence concerns the gene CRP and coronary artery disorder.