Investigators at the Dana Farber Cancer Institute (DFCI) reported the outcomes of 1490 patients with metastatic NSCLC whose tumors were genetically profiled by targeted NGS focusing on the six BAF genes most often altered in NSCLC (SMARCA4, ARID1A, ARID1B, ARID2, PBRM1, and SMARCB1) [16]. Here, SMARCB1 is linked to non-small cell lung carcinoma.