Second, a biomarker-positive result would alert clinicians to residual infection risk even if traditional markers are negative (e.g., synovial neutrophils, C-reactive protein, erythrocyte sedimentation rate) and result in more prompt and more aggressive management, for example by extending the course of antibiotics, revising surgical strategy to ensure more complete biofilm removal, or delaying re-implantation to give additional time for more durable infection control [72, 73]. Here, CRP is linked to infection.