To finally assess treatment efficacy of RAD51i due to ATRi-dysfunction, we used the chorioallantoic membrane (CAM) in ovo model, with the experimental timeline outlined in Fig. 7G. Tumor weights of p-SCCATRi+ RAD51i xenografts were significantly lower (16.8 mg) compared to p-SCC (26.5 mg) and p-SCCATRi (22.8 mg), and a similar trend was observed in the p-SCC + ATRi + RAD51i with 27.8 mg (Fig. 7H). Here, SERPINB3 is linked to neoplasm.