ACTG2 and cholelithiasis: The other ACTG2 variants (R63Q, R178C, R257H, and R257C) found in our cohort were significantly more likely to be associated with the need for decompression stomata (100%), parenteral nutrition (100%), and hepatobiliary complications (IFALD, 72.2%; cholelithiasis, 81.8%) than R40H and/or P39R (Fig. 4A; Table 2).