In addition, although NP mice exhibited significantly shorter tumor-free survival compared to N mice (Fig. 1a), and SAA1, SAA2, and THBS4 enhanced HER2/neu+ cancer cell proliferation in vitro (Fig. 4c), Ki67 staining of tumor sections did not reveal differences in proliferation between N and NP tumors. The gene discussed is SAA2; the disease is neoplasm.