Participants that developed dementia over the study period showed a positive correlation between baseline serum levels of IL-12p70 (r = 0.523, r = 0.486), and IL-8 (r = 0.468, r = 0.389) and IgG serum levels to the periodontal pathogens Td and Tf, respectively (Supplemental Figure 2). Here, TF is linked to dementia.