For example, mir-181 and mir-183 promote KRAS-driven tumorigenesis in pancreas and lung (Miao et al., 2016; Valencia et al., 2020; Yang et al., 2019), whereas mir-143 targets Kras and suppresses pancreatic ductal adenocarcinoma progression (Hu et al., 2012; Xie et al., 2019). The gene discussed is KRAS; the disease is pancreatic ductal adenocarcinoma.