On the other hand, ENKL is negative for CD4, CD8, and CD20, exhibiting a double negative T phenotype shared by peripheral T-cell lymphomas, not otherwise specified [3,13]. Although these tumors may also express CD56, the median age of presentation at 60 years, distinct clinical presentation, frequent nodal involvement, and lack of CD3 epsilon expression suggest that this diagnosis was unlikely in our patient [17]. Here, CD4 is linked to T-cell non-Hodgkin lymphoma.