SPP1 and cervical carcinoma: The results showed that the communication intensity of signaling pathways such as LCK, CEACAM, IFN-II, IL16, NECTIN, PTN, LAIR1, VCAM, HGF, and SPP1 increased significantly in the cervical cancer group; the communication intensity of signaling pathways such as ncWNT, CADM, RA, KIT, EGF, Histamine, NRG, CD46, and LXA4 increased significantly in the healthy control group (Figure 8b).