The outcomes demonstrated 35 genes were screened and selected as prognostic predictors, that LYZ, CRIP1, PPP1R14A, CHMP4C, ADCY4, CBX7, DES, ZNF280D, FEZ1, SPP1, CYTL1, RPL41P5, CA9, BAIAP2L1, AC103810.3, HOXA10, SKA3, HSPG2, RGS5, CCZ1, EEF1D, MCM5, RAB3IL1, and SPINT1 were independent variables for cervical cancer development and occurrence (p < 0.05, Figure 4b). This evidence concerns the gene DES and cervical cancer.