Initially, we reviewed the clinical data of patients, conducted univariate analysis, and combined with literature research on prognostic factors of pancreatic cancer, finally including 11 biological indicators (IL-2, IL-4, IL-6, IL-17, IFN-γ, NLR, LDH, CEA, AFP, CA19-9, β2-MG). This evidence concerns the gene IL4 and pancreatic neoplasm.