Combination of Serum Amyloid P-component (SAP), Alpha-1-Antitrypsin (AAT), Lactotransferrin (LT) content in plasma before ascension was higher in the severe AMS + group in comparison to the AMS- group, combination of SAP and HSP90-α – in the group with moderate course of AMS+ in comparison to AMS-, and combination of SAP and LT – in the group with severe course of AMS+ in comparison to moderate AMS+. Here, SERPINA1 is linked to ablepharon macrostomia syndrome.