DPT3f enhances FSP1/CoQ10 pathway antioxidant activity by upregulating FSP1 protein expression, promotes CoQ10 conversion to reduced CoQ10H2 to scavenge lipid peroxides, thus inhibiting dopaminergic neuron ferroptosis, protecting SN neurons and alleviating PD-related damage (230). This evidence concerns the gene AIFM2 and Parkinson disease.