In November 2024, tumor markers in blood were elevated, including CYFRA21-1 (cytokeratin 19 fragment, 13.86 ng/mL, normal value: 0–3.3 ng/mL), neuron-specific enolase (21.81 ng/mL, normal value: 0–16.3 ng/mL), and CEA (28.81 ng/mL, normal value: 0–5 ng/mL). The gene discussed is CEACAM5; the disease is neoplasm.