In the analysis of HER2-low or HER2-zero breast cancer, the utilization of the nomogram led to an AUC, sensitivity, specificity, and accuracy of 0.77 (95% CI: 0.68–0.86), 0.83 (95% CI: 0.66–0.97), 0.74 (95% CI: 0.66–0.83), and 0.76 (95% CI: 0.69–0.84) for Radiologist 2, and 0.81 (95% CI: 0.72–0.89), 0.86 (95% CI: 0.72–0.97), 0.77 (95% CI: 0.69–0.85), and 0.80 (95% CI: 0.72–0.86) for Radiologist 1, respectively (Table 4; Figure 5E). This evidence concerns the gene ERBB2 and breast carcinoma.