Independent predictors included hypertension (HR = 2.1, p = 0.01), female sex (HR = 1.8, p = 0.03), smoking (HR = 1.9, p = 0.02), and elevated B‐type natriuretic peptide (BNP) (HR = 3.4, p < 0.001). The gene discussed is NPPB; the disease is Hypertension.