C3AR1 and neoplasm: Furthermore, after treating tumor cells with the culture medium conditioned with Malassezia globosa‐treated THP‐1 cells for 24 h, proliferation, migration and invasion of MDA‐MB‐231 and MCF‐7 cells were all elevated and again reversed in the presence of the C3aR antagonist (p < 0.05, Figure 5E–G), thus reaffirming the activation of the MBL‐complement pathway by M. globosa.