Based on the function of TRIM47 in regulating the ubiquitination modification, to further elucidate the regulatory mechanism of TRIM47 in the progression of ICC, this study conducted an immunoprecipitation (IP) experiment using TRIM47 antibodies to isolate the binding partners of TRIM47, which were subsequently identified through mass spectrometry (MS) analysis. The gene discussed is TRIM47; the disease is intrahepatic cholangiocarcinoma.