The Nrf2, NQO1, and HO-1 mRNA expression levels were significantly reduced in the FLHS model group compared with the normal control group (p < 0.05), and after the intervention of adding taurine, the Nrf2, HO-1 mRNA expression levels increased significantly (p < 0.05), and NQO1 mRNA expression levels showed an increasing trend but not significant (p>0.05). This evidence concerns the gene NQO1 and Floating-Harbor syndrome.