It is noteworthy that biallelic pathogenic variants in TNNT3 are associated with congenital myopathies [59], different splice isoforms of the LDB3 have significant effects on chicken muscle atrophy and sarcomere formation [60], MYBPC1 knockout mice exhibit impaired skeletal muscle formation and structure after birth [61], and ACTN2 plays a pivotal role in muscle tissue and myopathies [62]. The gene discussed is ACTN2; the disease is myopathy.