In the dominant inheritance model, a strong association was observed between the ANRIL-CC genotype and the combined (CA + AA) genotypes with susceptibility to stroke, yielding an OR of 1.83 (95% CI = 1.0456 to 3.214), RR of 1.35 (95% CI = 0.9811 to 1.579), and a p-value less than 0.034. This evidence concerns the gene CDKN2B-AS1 and Stroke.