As per previous strudies highlighting the pathogenicity of the COL4A2 p.Glu1123Gly variant [52], our research also identified four of the most prevalent COL4A2 gene variants in our stroke patients: COL4A2 rs4238272 (c.297G > A), rs439831 (c.3804T > A), rs409858 (c.3807T > C), and rs438758 (c.4083T > C) (Table 8). Here, COL4A2 is linked to stroke disorder.