Our findings revealed a robust association between the ANRIL rs10757278 GG genotype and susceptibility to stroke in the codominant model, with an OR of 2.80 (95% CI = 1.3803 to 5.686), a RR of 1.66 (95% CI = 1.1611 to 2.388), and a p-value less than 0.004 (Table 5). Here, CDKN2B-AS1 is linked to Stroke.