In the codominant model, the PAI-1 -4G/5G genotype was associated with increased stroke risk, with an OR of 2.09 (95% CI = 1.0505 to 3.829), RR of 1.34 (1.0240 to 1.766), and a p-value of less than 0.034. Here, SERPINE1 is linked to stroke disorder.