Our findings demonstrated a significant association between the lncRNA ANRIL rs1333048-GA genotype and susceptibility to stroke in the codominant model, with an odds ratio (OR) of 2.29 (95% CI = 1.2465 to 4.213), a relative risk (RR) of 1.54 (95% CI = 1.1090 to 2.149), and a p-value of less than 0.007 (Table 4). The gene discussed is CDKN2B-AS1; the disease is stroke disorder.