We observed that the number of total leukocytes (CD45+) in the PA was positively correlated with the arthritis scores; r = 0.5143, n = 23, p = 0.006 (Fig 5A), and the monocytes/macrophages and neutrophils (CD11b/c+) in the PA were positively correlated with the arthritis scores; r = 0.6474, n = 23, p = 0.0004 (Fig 5B). This evidence concerns the gene ITGAM and arthritic joint disease.