CASP3 and pancreatic ductal adenocarcinoma: In pancreatic ductal adenocarcinoma, increased miR-184 promotes apoptosis via caspase-3/9 activation and Bcl-2 downregulation [11], while lymphomas show suppression through inhibition of RasL10B, TNFAIP8, and iASPP, promoting apoptosis [15, 51].