It has been implicated in tumor growth, invasion, and metastasis. Like CD47, CD24 is also a “don’t eat me signal”, acting as an inhibitor for Siglec-10 on macrophages and other immune cells. Furthermore, CD24 has been recognized as a marker for cancer stem cells, which are a small cell subpopulation within tumors that are notorious for their ability to self-renew and drive tumor recurrence. These cells are thought to be responsible for tumor recurrence and resistance to both chemotherapy and radiation therapy. This evidence concerns the gene CD24 and neoplasm.