TMBIM6, a key regulator of stress responses, is linked to increased chemoresistance, cancer progression, and metastasis in breast cancer, as well as reduced patient survivalTMBIM6, a key regulator of stress responses, is linked to increased chemoresistance, cancer progression, and metastasis in breast cancer, as well as reduced patient survival (Robinson et al., 2025). The gene discussed is TMBIM6; the disease is breast cancer.