M5 expressed pericyte-associated genes (RGS5, PDGFRB, NES, THY1, KCNJ8) and showed strong similarity to curated pericyte signatures, including pan-cancer C8_RGS5 pericytes, healthy human prostate pericytes and pericytes from lung cancer (Chen et al., 2022; Joseph et al., 2021; Kim et al., 2020; Qian et al., 2020) (Figures 2A,C; Supplementary Figures S1E,G,I). Here, RGS5 is linked to cancer.