Supportively, CD90+SMA+ cells were observed in the wall of small vessels but not in the multi-layered wall of larger vessels (Figure 7A) with SMA immunostaining employed to identify SMC due to decreased MCAM immunofluorescence of PSMC in PCa tissues (Figures 2E,H; Supplementary Figure S7A). This evidence concerns the gene MCAM and posterior cortical atrophy.