PLOD1 and testicular germ cell tumor: In one study, 41% of cured non-seminomatous testicular germ cell tumor patients were found to have false-positive beta-HCG elevations due to cross-reactivity with LH [20]. Current advanced beta-HCG diagnostic testing uses an electro-chemiluminescent immunoassay, which has a much lower cross-reactivity rate of 0.12% with LH [21].