Thalamic–basal ganglia GBM cases exhibited recurrent chromosomal imbalance (chromosomal 7+/10–, 46.2%), PTEN deletions (41.2%), and lower frequencies of TERTp mutation (27.8%) and EGFR amplification (22.2%) (Fig. 5K). The gene discussed is EGFR; the disease is glioblastoma.