The exome analysis identified several candidate genes related to T1D, like human leukocyte antigen (HLA), insulin (INS) gene, Cytotoxic T-lymphocyte–Associated Protein 4 (CTLA4), Protein Tyrosine Phosphatase Nonreceptor Type 22 (PTPN22), and Interferon-Induced Helicase C Domain 1 (IFIH1). This evidence concerns the gene INS and type 1 diabetes mellitus.