To assess the potential effects of COVID-19 on the peripheral blood CM and EM Th cell subsets, we analyzed main ‘polarized’ Th subsets within CD45RA–CCR7+ and CD45RA–CCR7– Th cells, that recirculate through blood, lymphatic system and secondary lymphoid organs, or migrate to inflamed peripheral tissues (44). This evidence concerns the gene CCR7 and COVID-19.