sLAG-3 might inhibit the tumor growth, and promote the secretion of CD8+T cells, IL-12 and IFN-γ (309)A combination of cyclosporin-A and IFN-γ induces apoptosis in human gastric carcinoma cells (310)IFN-gamma suppressed cell growth through induction of both cell cycle arrest and apoptosis (311). This evidence concerns the gene CD8A and neoplasm.