IL-23 was released in the presence of H. pylori from the inflamed gastric mucosa, which was positively correlated with neutrophil and monocyte infiltration (166)IL-23 plays a role in the activation of the immune response and induction of gastritis in response to H. pylori by contributing to the control of infection and severity of gastritis (167)Upregulation of IL-23 occurs early in the host response to H. pylori and may contribute to the severity of induced gastric lesions (168)A role for RUNX3 in inflammation-induced expression of IL23A in gastric epithelial cells (169). Here, IL23A is linked to gastritis.