pylori infection, IL-1β is highly expressed that result in gastric acid inhibition, GC -related gene methylations and disfunctions, angiogenesis (113)IL-1 Up-regulates MicroRNA 135b to Promote Inflammation-Associated Gastric Carcinogenesis in Mice (114)IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance (115). This evidence concerns the gene IL1B and cancer.