CD8A and nonpapillary renal cell carcinoma: Whereas in the high expression RELT group, there was a difference between the group with low hematopoietic stem cells, macrophage M1, macrophage M2, myeloid dendritic cell activated, T cell CD8+ central memory, T cell CD8, and neutrophil’s group and the group with higher MDSC that tended to be accompanied by a worse prognosis, we suggest that RELT may enhance immune escape from ccRCC by inhibiting T cells and promoting suppression of the immune response to MDSC (Figure 5E).