Taken together, the above data show that the expression of RELT in ccRCC is significantly elevated, and the expression of RELT is closely related to the clinical data of patients, survival time, and other factors, and it predicts a poor prognosis, and the expression level of RELT in the population can be used to diagnose patients with ccRCC with a high degree of reliability, which suggests that RELT can be used as a new biomarker for the diagnosis of ccRCC. Here, RELT is linked to nonpapillary renal cell carcinoma.