Specifically, anti-HER2/neu TCR T cells induced 61 ± 19% lysis of SK-MEL-5 and SK-MEL-37 cells, compared to the 16 ± 10% cell lysis for HCT-116, MDA-MB-231, and the non-transfected T-cells co-cultured with these tumor cell lines representing a 3.7-fold cell lysis difference (mean ± SD, n = 14 with 3 technical replicates). Here, ERBB2 is linked to neoplasm.