As for the SK-MEL-5 and SK-MEL-37 melanoma lines, peer-reviewed publications explicitly reporting HER2 surface expression by flow cytometry or other methods are limited, public proteomic datasets and cell-line databases indicate detectable HER2 protein levels in SK-MEL-5 (29, 30), and some studies have shown that a subset of melanoma cell lines can express HER2 (29–31). Here, ERBB2 is linked to melanoma.