CXCR2 and epidermolysis bullosa: Biopsy samples from skin with blisters in EB patients reveal elevated levels of chemokine receptors such as CXCR1, CXCR2, CCR2, and CCR4, along with dense infiltration of epidermal neutrophils (CXCR2+ CD11b+ CD16+), which make up the majority of the white blood cells (up to 90%) (124–126).