Similarly, in a rabbit model of atherosclerosis, supplementation with jaboticaba (P. cauliflora) peel decreased plasma levels of IL-1β, IL-6, and soluble intercellular adhesion molecule-1 (sICAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1) and reduced atherosclerotic lesions [27]. The gene discussed is ICAM1; the disease is Atherosclerotic lesion.