Notably, 5,7,4′-trimethoxyflavone and 5,7-dimethoxyflavone have demonstrated potent inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), suggesting their therapeutic potential in treating Alzheimer’s disease [31]. The gene discussed is BCHE; the disease is early-onset autosomal dominant Alzheimer disease.