Ishihara et al. (2017) [30] analyzed the levels of various proteins, including some previously reported as potential biomarkers for eosinophilic esophagitis, such as interleukin 5 (IL-5) and interleukin 33 (IL-33); however, they were not significantly elevated in EoE patients. This evidence concerns the gene IL33 and eosinophilic esophagitis.